Basic Information

Symbol
hsa-miR-551b-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-551b MIR551B MicroRNA 551b
Location (GRCh38)
-
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-551b-5p
Sequence length
22 nt
GC content
0.5455
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the miR-551b-5p being downregulated in hypertrophic scar tissue versus normal skin [Siu et al. DOI:10.1111/wrr.13100]. In a separate forensic investigation using postmortem human serum, exosomal miRNA expression profiling revealed the miR-551b-5p was significantly upregulated (2.64-fold) in acute myocardial infarction cases compared to hemorrhagic shock controls [Kanno et al. DOI:10.1007/S00414-022-02913-Y].