Basic Information

Symbol
hsa-mir-553
RNA class
miRNA miRNA hairpin
Alias
MIR553 MicroRNA 553 Hsa-Mir-553 MIRN553 MIMAT0003216 Hsa-MiR-553 MI0003558
Location (GRCh38)
19:10817426-10817496
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Drug abuse diagnoses
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-553
Sequence length
68 nt
GC content
0.3235

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-25.20 kcal/mol
Thermodynamic ensemble
Free energy: -25.93 kcal/mol
Frequency: 0.3995
Diversity: 1.93
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.......((((.(((((((((((((((((((.((......)).))))))))))))))))))).)))),
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-553 is involved in drug response, with its expression increased by chronic intermittent alcohol exposure in the brain [Zhao et al. DOI:10.1007/s11411-016-9671-z].