Basic Information
Symbol
hsa-miR-553
RNA class
miRNA
mature miRNA
Alias
hsa-miR-553
MIR553
MicroRNA 553
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-25.20 kcal/mol
Thermodynamic ensemble
Free energy:
-25.93 kcal/mol
Frequency:
0.3995
Diversity:
1.93
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.......((((.(((((((((((((((((((.((......)).))))))))))))))))))).)))),
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-553 is involved in drug response, with its expression increased by chronic intermittent alcohol exposure in the brain [Zhao et al. DOI:10.1007/s11411-016-9671-z].