Basic Information

Symbol
hsa-mir-556
RNA class
miRNA miRNA hairpin
Alias
MIR556 MicroRNA 556 Hsa-MiR-556-5p Hsa-MiR-556-3p Hsa-Mir-556 MIRN556 Hsa-Mir-556_pre MIMAT0004793 MIMAT0003220 MI0003562 Mir-556
Location (GRCh38)
1:1167104-1167198
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-556
Sequence length
95 nt
GC content
0.2737

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.90 kcal/mol
Thermodynamic ensemble
Free energy: -38.23 kcal/mol
Frequency: 0.1162
Diversity: 3.25
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((((((((((((((((((.((.((((((((((..............)))))))))).)).))))))))))))))))))))).........
Thermodynamic Ensemble Prediction
{.(((((((((((((((((((((.((.((((((((((..............)))))))))).)).))))))))))))))))))))).........
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-thermal injury [Siu et al. DOI:10.1111/wrr.13100]. A study in humans identified the mir-556-3p as one of seven miRNAs downregulated in healthy controls but upregulated in patients with atrial fibrillation across baseline, 12-month, and 24-month follow-up periods through time series analysis [Wang et al. DOI:10.1016/j.hrtlng.2020.03.021].