Basic Information
Symbol
hsa-miR-557
RNA class
miRNA
mature miRNA
Alias
hsa-miR-557
MIR557
MicroRNA 557
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.80 kcal/mol
Thermodynamic ensemble
Free energy:
-32.03 kcal/mol
Frequency:
0.0270
Diversity:
14.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....((..(....)..)).....(((((((((..(((((((.((((((((((.....))))...))).))).))))))))))))))))..........
Thermodynamic Ensemble Prediction
.....,..,.......||.....(((((((((..{((((((.((((((,(({.....}}}}...))).))).))))))})))))))))......,,..
Forensic Context
A study in humans identified the miR-557 as significantly upregulated, showing a 9.60-fold increase in denatured dermis from deep partial-thickness burn patients compared to paired normal skin [Liang et al. DOI:10.1016/j.burns.2011.10.014]. A subsequent review confirmed this finding, reporting the miR-557 was upregulated in human deep partial-thickness burn skin four days post-injury [Siu et al. DOI:10.1111/wrr.13100].