Basic Information

Symbol
hsa-mir-558
RNA class
miRNA miRNA hairpin
Alias
MIR558 MicroRNA 558 Hsa-Mir-558 Hsa-MiR-558 MIRN558 MIMAT0003222 MI0003564
Location (GRCh38)
2:135665397-135665478
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-558
Sequence length
94 nt
GC content
0.4255

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.90 kcal/mol
Thermodynamic ensemble
Free energy: -45.77 kcal/mol
Frequency: 0.2421
Diversity: 4.75
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans with coronary artery disease identified the mir-558 as differentially expressed in whole blood, where it was downregulated in patients with recurrent myocardial infarction after percutaneous coronary intervention compared to those without recurrent events, with this association remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307].