Basic Information
Symbol
hsa-miR-558
RNA class
miRNA
mature miRNA
Alias
hsa-miR-558
MIR558
MicroRNA 558
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.90 kcal/mol
Thermodynamic ensemble
Free energy:
-45.77 kcal/mol
Frequency:
0.2421
Diversity:
4.75
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
........((.(((.((((((.((((((((((((((((((..((..(((...)))..))..)))))))))))))))))))))))).))).))..
Thermodynamic Ensemble Prediction
........((.(((.((((({,((((((((((((((((((..((..(((...)))..))..)))))))))))))))))))))))).))).))..
Forensic Context
A study in humans with coronary artery disease identified the miR-558 as differentially expressed in whole blood, where it was downregulated in patients with recurrent myocardial infarction after percutaneous coronary intervention compared to those without recurrent events, with this association remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307].