Basic Information

Symbol
hsa-mir-5580
RNA class
miRNA miRNA hairpin
Alias
MIR5580 MicroRNA 5580 Hsa-Mir-5580 MIMAT0022273 MIMAT0022274 MI0019135
Location (GRCh38)
14:53948427-53948484
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-5580
Sequence length
58 nt
GC content
0.4310

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.50 kcal/mol
Thermodynamic ensemble
Free energy: -39.23 kcal/mol
Frequency: 0.3050
Diversity: 2.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs showing altered expression in human skin tissue samples post-burn, during wound healing, and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans identified 977 differentially expressed genes in blood from myocardial infarction patients, with mir-5580 being one of the top 10 upregulated DEGs and its expression trend was consistent in an independent validation dataset [Zhao et al. DOI:10.3892/etm.2017.5580].