Basic Information

Symbol
hsa-mir-1273h
RNA class
miRNA miRNA hairpin
Alias
MIR1273H MicroRNA 1273h Hsa-Mir-1273h MicroRNA Mir-1273h Hsa-MiR-1273h-3p Hsa-MiR-1273h-5p MIMAT0030416 MIMAT0030415 MI0025512
Location (GRCh38)
16:24203116-24203231
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Drug abuse diagnoses
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1273h
Sequence length
116 nt
GC content
0.5690

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-76.80 kcal/mol
Thermodynamic ensemble
Free energy: -77.69 kcal/mol
Frequency: 0.2351
Diversity: 3.11
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((.....(((.((((((((((((((((((((((((.((.((((((((...((....))...)))))))).)).))))))))))))))))))))))))))))))))))))
Thermodynamic Ensemble Prediction
{((((((((.....(((.((((((((((((((((((((((((.((.((((((((...((....))...)))))))).)).)))))))))))))))))))))))))))))))))))}
Forensic Context

A study in humans demonstrated that the mir-1273h is differentially expressed in peripheral blood between monozygotic twins, as identified by miRNA sequencing and validated by droplet digital PCR (ddPCR), which showed superior recognition accuracy for distinguishing individuals [Wang et al. DOI:10.1016/j.fsigen.2025.103230]. A separate pilot study in humans found the mir-1273h to be hypermethylated in the postmortem nucleus accumbens of subjects with alcohol use disorder compared to controls [Liu & Zhang DOI:10.3390/genes13060958].