Forensic Context

A study in mice demonstrated that the miR-574-5p was identified as a core microRNA with a degree of 92 in a co-expression network, where it was positively correlated with mRNAs Tmed8 and Ctsz, and its expression was validated by qRT-PCR in the context of chronic intermittent hypoxia-exaggerated post-myocardial infarction cardiac remodeling [Wang et al. DOI:10.3389/fgene.2022.818823]. In human studies, the miR-574-5p was predicted to bind to the upregulated circRNA hsa_circRNA_103899 in both plasma and lung tissue from patients with sepsis-induced acute respiratory distress syndrome [Guo et al. DOI:10.1016/j.lfs.2021.119566]. A study in mice demonstrated that the miR-574-5p was identified as a key differentially expressed miRNA regulator targeting the candidate fracture healing marker Col6a1 [Li et al. DOI:10.1155/2021/2866475].