Basic Information

Symbol
hsa-mir-576
RNA class
miRNA miRNA hairpin
Alias
MIR576 MicroRNA 576 Hsa-MiR-576-5p Hsa-MiR-576-3p Hsa-Mir-576 MIRN576 Hsa-Mir-576_pre MIMAT0004796 MIMAT0003241 MI0003583
Location (GRCh38)
14:100869060-100869148
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Chronological age estimation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-576
Sequence length
98 nt
GC content
0.3673

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-46.50 kcal/mol
Thermodynamic ensemble
Free energy: -46.99 kcal/mol
Frequency: 0.4494
Diversity: 2.35
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((.((.((((((((((((((.((((((((((((.(((......))).)))))))))))).)))))))))))))).)).)))))..........
Thermodynamic Ensemble Prediction
..(((((.((.((((((((((((((.((((((((((((.(((......))).)))))))))))).)))))))))))))).)).)))))..........
Forensic Context

A review of human studies identified 197 miRNAs associated with altered expression in human skin following burns, during wound healing, and in scarring, with specific dysregulation patterns validated by qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A review of multi-omics studies in humans identified the mir-576-3p as a microRNA with a negative correlation to chronological age [Solovev et al. DOI:10.1016/j.mad.2019.111192].