Basic Information

Symbol
hsa-mir-578
RNA class
miRNA miRNA hairpin
Alias
MIR578 MicroRNA 578 Hsa-Mir-578 MIRN578 MIMAT0003243 Hsa-MiR-578 MI0003585
Location (GRCh38)
Forensic tag(s)
Other applications

Sequence & Structure

Transcript ID
hsa-mir-578
Sequence length
96 nt
GC content
0.3438

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-41.60 kcal/mol
Thermodynamic ensemble
Free energy: -42.65 kcal/mol
Frequency: 0.1830
Diversity: 5.30
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-578 as a potential biomarker predicted to bind the up-regulated circRNAs hsa_circRNA_104700 and hsa_circRNA_102315 in sepsis-induced acute respiratory distress syndrome [Guo et al. DOI:10.1016/j.lfs.2021.119566]. A separate review highlighted that in human breast cancer, circZFR promotes progression via a miR-578/HIF1A axis [Huang et al. DOI:10.3390/cells11091381].