Basic Information

Symbol
hsa-mir-579
RNA class
miRNA miRNA hairpin
Alias
MIR579 MicroRNA 579 Hsa-MiR-579-3p Hsa-Mir-579 MIRN579 Hsa-Mir-579_pre Hsa-MiR-579-5p MIMAT0003244 MIMAT0026616 MI0003586
Location (GRCh38)
X:152392219-152392299
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-579
Sequence length
98 nt
GC content
0.3265

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.10 kcal/mol
Thermodynamic ensemble
Free energy: -50.11 kcal/mol
Frequency: 0.1937
Diversity: 4.65
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human postmortem prefrontal cortex tissue demonstrated that the mir-579 was significantly up-regulated (2.06-fold) in subjects with bipolar disorder compared to non-psychiatric controls [Smalheiser et al. DOI:10.1371/journal.pone.0086469]. A separate review noted that the mir-579 was also reported to be upregulated in patients with a major depressive episode [Miguel et al. DOI:10.1089/Ars.2017.7175].