Basic Information
Symbol
hsa-mir-580
RNA class
miRNA
miRNA hairpin
Alias
MIR580
MicroRNA 580
Hsa-Mir-580
Hsa-MiR-580-3p
MIRN580
Hsa-Mir-580_pre
Hsa-MiR-580-5p
MIMAT0003245
MIMAT0026617
MI0003587
Location (GRCh38)
7:100093768-100093847
Forensic tag(s)
Wound age identification
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.60 kcal/mol
Thermodynamic ensemble
Free energy:
-48.23 kcal/mol
Frequency:
0.3596
Diversity:
1.90
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....((((((..((((((((((((((((((((((..((((((((((.........))))))))))..))))))))))))))))))))))..))))))
Thermodynamic Ensemble Prediction
....{(((((..((((((((((((((((((((((..((((((((((.........))))))))))..))))))))))))))))))))))..)))))}
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like hsa-miR-21 and hsa-miR-31 shown to promote keratinocyte proliferation and migration and be upregulated in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A systematic review of human studies found that the mir-580-3p is associated with traffic-related air pollution (TRAP) component exposure, specifically with PM10, PM2.5, black carbon, ultrafine particles, and NO2 in plasma [Kotsyfakis & Patelarou 10.1080/1354750X.2019.1652348].