A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like hsa-miR-21 and hsa-miR-31 shown to promote keratinocyte proliferation and migration and be upregulated in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A systematic review of human studies found that the miR-580-3p is associated with traffic-related air pollution (TRAP) component exposure, specifically with PM10, PM2.5, black carbon, ultrafine particles, and NO2 in plasma [Kotsyfakis & Patelarou 10.1080/1354750X.2019.1652348].