Basic Information

Symbol
hsa-mir-585
RNA class
miRNA miRNA hairpin
Alias
MIR585 MicroRNA 585 Hsa-Mir-585 Hsa-MiR-585-3p MIRN585 Hsa-Mir-585_pre Hsa-MiR-585-5p MIMAT0003250 MIMAT0026618 MI0003592 Mir-585
Location (GRCh38)
5:169263601-169263694
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-585
Sequence length
94 nt
GC content
0.5426

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-55.70 kcal/mol
Thermodynamic ensemble
Free energy: -56.73 kcal/mol
Frequency: 0.1892
Diversity: 4.62
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-585-3p was selected as a candidate for semen identification but showed no specific amplification in pooled samples [Sauer et al. DOI:10.1016/j.fsigen.2016.01.018]. A separate review of human studies found that the mir-585-3p was incorporated into a multivariate model for Brugada syndrome, achieving a high predictive capacity for major cardiac events with an AUC of 0.96 [Raluca-Maria Cătinas et al. DOI:10.3390/ijms26146818].