Basic Information

Symbol
hsa-mir-588
RNA class
miRNA miRNA hairpin
Alias
MIR588 MicroRNA 588 Hsa-Mir-588 Hsa-MiR-588 MIRN588 MIMAT0003255 MI0003597
Location (GRCh38)
6:126484631-126484713
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-588
Sequence length
83 nt
GC content
0.4458

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.10 kcal/mol
Thermodynamic ensemble
Free energy: -44.39 kcal/mol
Frequency: 0.1237
Diversity: 3.82
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the mir-588 being significantly upregulated in deep partial thickness burn skin four days post-burn compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-588 is among miRNAs uniquely detected in semen fluids [Shimaa Ahmed Alsaeed et al. DOI:10.1007/s12024-024-00831-6].