Basic Information
Symbol
hsa-miR-588
RNA class
miRNA
mature miRNA
Alias
hsa-miR-588
MIR588
MicroRNA 588
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
Wound age identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.10 kcal/mol
Thermodynamic ensemble
Free energy:
-44.39 kcal/mol
Frequency:
0.1237
Diversity:
3.82
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the miR-588 being significantly upregulated in deep partial thickness burn skin four days post-burn compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-588 is among miRNAs uniquely detected in semen fluids [Shimaa Ahmed Alsaeed et al. DOI:10.1007/s12024-024-00831-6].