Basic Information

Symbol
hsa-mir-593
RNA class
miRNA miRNA hairpin
Alias
MIR593 MicroRNA 593 Hsa-MiR-593-5p Hsa-Mir-593 Hsa-MiR-593-3p MIRN593 MIMAT0004802 MIMAT0003261 MI0003605
Location (GRCh38)
7:128081861-128081960
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-593
Sequence length
100 nt
GC content
0.6100

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-41.90 kcal/mol
Thermodynamic ensemble
Free energy: -42.85 kcal/mol
Frequency: 0.2133
Diversity: 26.79
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((((.......((((.((.((((.((((((((((.....(((((((....)))))))...)))))))))).)))).)).))))))))))........
Thermodynamic Ensemble Prediction
.((((((.....,.(((({{(,((((.{(({((((((..,,,({{{{{{...,))})))),..)})))))))),))))})}}}},,))))))........
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns validated in human skin tissue and cell lines using qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A review of human miRNA profiling for forensic body fluid identification notes that mir-593 was found down-regulated in serum in lung cancer [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002].