Basic Information

Symbol
hsa-mir-597
RNA class
miRNA miRNA hairpin
Alias
MIR597 MicroRNA 597 Hsa-MiR-597-5p Hsa-Mir-597 MIRN597 Hsa-MiR-597-3p MIMAT0003265 MIMAT0026619 MI0003609 Mir-597
Location (GRCh38)
15:31065032-31065141
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-597
Sequence length
97 nt
GC content
0.4433

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.40 kcal/mol
Thermodynamic ensemble
Free energy: -37.29 kcal/mol
Frequency: 0.0463
Diversity: 16.90
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((((((((((.((((((((..((.(((((((((....(((......)))))))))))).))..)))))....)))..))))))))))..))).
Thermodynamic Ensemble Prediction
.(((((((((((((.((.(((((..((.(((((((((,...{((......)))))))))))).))..))))).},.))),,,}))))))))..,,,.
Forensic Context

A study in humans demonstrated that the mir-597 was significantly decreased (0.628 of control) in the prefrontal cortex of depressed suicide subjects [Smalheiser et al. DOI:10.1371/journal.pone.0033201], while a separate human study found it was upregulated (4-fold increase) in the urine of farmworker adults during the post-harvest season and showed a positive dose-response trend with organophosphate pesticide metabolites [Weldon et al. DOI:10.1016/J.Taap.2016.01.018].