Basic Information

Symbol
hsa-mir-599
RNA class
miRNA miRNA hairpin
Alias
MIR599 MicroRNA 599 Hsa-Mir-599 MIRN599 Hsa-Mir-599_pre MIMAT0003267 Hsa-MiR-599 MI0003611
Location (GRCh38)
11:2134134-2134209
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-599
Sequence length
95 nt
GC content
0.4211

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.90 kcal/mol
Thermodynamic ensemble
Free energy: -40.70 kcal/mol
Frequency: 0.0542
Diversity: 7.65
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
..........,(((((.((((((((((((((((((((((..((((({((.....,)).))))))))))))))))))))),.})))))))))),..
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scars [Siu et al. DOI:10.1111/wrr.13100]. A study in rhesus macaques demonstrated that the mir-599 was utilized as a feature in a four-group survival prediction model at Day 3 post-thoracic irradiation [May et al. DOI:10.1038/s41598-022-16316-x].