Basic Information

Symbol
hsa-miR-618
RNA class
miRNA mature miRNA
Alias
hsa-miR-618 MIR618 MicroRNA 618
Location (GRCh38)
-
Forensic tag(s)
Other applications
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-618
Sequence length
23 nt
GC content
0.3913

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.00 kcal/mol
Thermodynamic ensemble
Free energy: -35.68 kcal/mol
Frequency: 0.0659
Diversity: 8.08
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((((((((..((((.((.((((((.((((((((.....(((.........))))))))))))))))).))))))...))))))))))).....
Thermodynamic Ensemble Prediction
..(((((((((((..((((.((.((((({,((((((((.....{{{,,....,,.))})))))))))))))).))))))...))))))))))).....
Forensic Context

A study in humans demonstrated that hsa-miR-618 was upregulated in the peripheral blood of severely injured patients in hemorrhagic shock, showing a 7.3-fold increase compared to healthy controls upon initial measurement and remaining elevated at 24 and 48 hours after ICU admission [Galbraith et al. DOI:10.1016/j.surg.2018.05.042]. In a separate human study on sepsis, hsa-miR-618 was identified as part of a competing endogenous RNA regulatory network, where it was computationally predicted to interact with the mRNA of core prognostic genes IL2RB and TGFBR3 [Zhang et al. DOI:10.1186/s12920-023-01460-8].