Basic Information

Symbol
hsa-mir-622
RNA class
miRNA miRNA hairpin
Alias
MIR622 MicroRNA 622 Hsa-Mir-622 Hsa-MiR-622 MIRN622 MIMAT0003291 MI0003636
Location (GRCh38)
13:90231182-90231277
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-622
Sequence length
96 nt
GC content
0.5208

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.30 kcal/mol
Thermodynamic ensemble
Free energy: -34.49 kcal/mol
Frequency: 0.5820
Diversity: 3.47
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....(((......(((.(((((((((((((((((.(((((.(((....))).)).)).).))))))))))))))))).))))))...........
Thermodynamic Ensemble Prediction
.......((.{.{.{((.(((((((((((((((((.(((((.(((....))).)).)).}.))))))))))))))))).)))},).}}........
Forensic Context

A study in mice demonstrated that the mir-622 promotes lung adenocarcinoma migration and invasion via the miR-622/HIF-1α axis [Huang et al. DOI:10.3390/cells11091381]. A study in humans using massively parallel sequencing identified 90 absolute specific markers (ASMs) for body fluid/tissue identification, including various miRNAs, piRNAs, and snoRNAs, but the mir-622 was not selected as an ASM in this experimental analysis [Liu et al. DOI:10.3390/genes13091530]. A subsequent review noted the mir-622 has been reported in published data as a specific marker for saliva [Liu et al. DOI:10.1007/s00414-025-03656-2].