Basic Information
Symbol
hsa-miR-622
RNA class
miRNA
mature miRNA
Alias
hsa-miR-622
MIR622
MicroRNA 622
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.30 kcal/mol
Thermodynamic ensemble
Free energy:
-34.49 kcal/mol
Frequency:
0.5820
Diversity:
3.47
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....(((......(((.(((((((((((((((((.(((((.(((....))).)).)).).))))))))))))))))).))))))...........
Thermodynamic Ensemble Prediction
.......((.{.{.{((.(((((((((((((((((.(((((.(((....))).)).)).}.))))))))))))))))).)))},).}}........
Forensic Context
A study in mice demonstrated that the miR-622 promotes lung adenocarcinoma migration and invasion via the miR-622/HIF-1α axis [Huang et al. DOI:10.3390/cells11091381]. A study in humans using massively parallel sequencing identified 90 absolute specific markers (ASMs) for body fluid/tissue identification, including various miRNAs, piRNAs, and snoRNAs, but the miR-622 was not selected as an ASM in this experimental analysis [Liu et al. DOI:10.3390/genes13091530]. A subsequent review noted the miR-622 has been reported in published data as a specific marker for saliva [Liu et al. DOI:10.1007/s00414-025-03656-2].