Basic Information

Symbol
hsa-mir-627
RNA class
miRNA miRNA hairpin
Alias
MIR627 MicroRNA 627 Hsa-MiR-627-5p Hsa-Mir-627 Hsa-MiR-627-3p MIRN627 MIMAT0026623 MIMAT0003296 MI0003641 Mir-627
Location (GRCh38)
12:6963699-6963766
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-627
Sequence length
97 nt
GC content
0.3505

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-55.50 kcal/mol
Thermodynamic ensemble
Free energy: -56.44 kcal/mol
Frequency: 0.2165
Diversity: 2.02
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((((.((((((((((((((.((((((((((((((.((....)).)))))))))))))).)))))))))))))).)))))))...........
Thermodynamic Ensemble Prediction
..(((((((.((((((((((((((.{(((((((((((((.{{....}}.)))))))))))))}.)))))))))))))).)))))))...........
Forensic Context

A study in rhesus macaques demonstrated that the mir-627 was identified as a circulating miRNA whose relative abundance at day 2 post-total-body irradiation correlated with the time to severe neutropenia, forming part of an 11-miRNA panel for predicting this hematopoietic injury [Rogers et al. DOI:10.1667/RADE-21-00043.1]. In a separate investigation in the same species, the mir-627 was utilized as a feature in a four-group survival prediction model developed from serum samples at day 3 post whole thorax irradiation [May et al. DOI:10.1038/s41598-022-16316-x].