Basic Information

Symbol
hsa-mir-628
RNA class
miRNA miRNA hairpin
Alias
MIR628 MicroRNA 628 Hsa-MiR-628-3p Hsa-MiR-628-5p Hsa-Mir-628 MIRN628 Hsa-Mir-628_pre MIMAT0003297 MIMAT0004809 MI0003642 Mir-628
Location (GRCh38)
15:55372940-55373034
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-628
Sequence length
95 nt
GC content
0.4105

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.60 kcal/mol
Thermodynamic ensemble
Free energy: -36.53 kcal/mol
Frequency: 0.2216
Diversity: 4.24
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-628 as significantly associated with activity of daily living fatigue scores, where a negative beta coefficient indicated decreased functionality with higher expression, and this association was validated in both individual and twin-pair level cross-sectional analyses [La Grotta et al. DOI:10.1016/j.mad.2025.112099]. In Wistar rats, the mir-628 was the most significantly upregulated miRNA in skeletal muscle three days after a severe burn injury, suggesting a potential role in the pathogenesis of skeletal muscle wasting [Zhang et al. DOI:10.5505/tjtes.2015.80707].