Basic Information

Symbol
hsa-mir-636
RNA class
miRNA miRNA hairpin
Alias
MIR636 MicroRNA 636 Hsa-Mir-636 Hsa-MiR-636 MIRN636 MIMAT0003306 MI0003651
Location (GRCh38)
17:76736450-76736548
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-636
Sequence length
99 nt
GC content
0.7879

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.30 kcal/mol
Thermodynamic ensemble
Free energy: -55.16 kcal/mol
Frequency: 0.3939
Diversity: 3.58
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((.(((((((.....((..(((((((((((.(((..(((.((..((......))..)).)))...))).))))))))))).))))))))).))....
Thermodynamic Ensemble Prediction
..((.(((((((.....{{.,(((((((((((.(((..(((.((..((......)),.)).)))...))).))))))))))).))))))))).))....
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scars [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-636 is downregulated in patients with a major depressive episode [Miguel et al. DOI:10.1089/Ars.2017.7175].