Basic Information
Symbol
hsa-miR-636
RNA class
miRNA
mature miRNA
Alias
hsa-miR-636
MIR636
MicroRNA 636
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
Forensic psychiatry evaluation
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.30 kcal/mol
Thermodynamic ensemble
Free energy:
-55.16 kcal/mol
Frequency:
0.3939
Diversity:
3.58
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((.(((((((.....((..(((((((((((.(((..(((.((..((......))..)).)))...))).))))))))))).))))))))).))....
Thermodynamic Ensemble Prediction
..((.(((((((.....{{.,(((((((((((.(((..(((.((..((......)),.)).)))...))).))))))))))).))))))))).))....
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scars [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the miR-636 is downregulated in patients with a major depressive episode [Miguel et al. DOI:10.1089/Ars.2017.7175].