Basic Information

Symbol
hsa-mir-638
RNA class
miRNA miRNA hairpin
Alias
MIR638 MicroRNA 638 Hsa-Mir-638 Hsa-MiR-638 MIRN638 MIMAT0003308 MI0003653
Location (GRCh38)
7:5495819-5495917
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-638
Sequence length
100 nt
GC content
0.8100

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.60 kcal/mol
Thermodynamic ensemble
Free energy: -56.16 kcal/mol
Frequency: 0.0794
Diversity: 20.44
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.......(((((.((((..(.(((.((((((((((((((..((.(((.....)))..))......))).))))..)).))))).))))..)))).)))))
Thermodynamic Ensemble Prediction
.......(((((.((((..{.(((.((((((({((({({...{,({({...,|||..|||....,))}.)))).,}).))))).)))}..)))).)))))
Forensic Context

A study in humans demonstrated that hsa-miR-638 was significantly up-regulated (4.11-fold) in denatured dermis from deep burn patients compared to paired normal skin [Liang et al. DOI:10.1016/j.burns.2011.10.014]. Another study in humans found that serum levels of the mir-638 were significantly upregulated in patients with mild traumatic brain injury at baseline following injury, with its expression progressively reducing at 24 and 48 hours, and it was also differentially expressed between mTBI patients and those with other injuries [Polito et al. DOI:10.1007/s11033-020-05386-7].