Basic Information

Symbol
hsa-mir-639
RNA class
miRNA miRNA hairpin
Alias
MIR639 MicroRNA 639 Hsa-Mir-639 Hsa-MiR-639 MIRN639 MIMAT0003309 MI0003654
Location (GRCh38)
19:14529543-14529640
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-639
Sequence length
98 nt
GC content
0.7347

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.10 kcal/mol
Thermodynamic ensemble
Free energy: -45.58 kcal/mol
Frequency: 0.0903
Diversity: 9.95
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((...(.(((((.(((((((.(.((.((..((((((((((......)))))).)))).)).)).)))))))).))))).)...).))).......
Thermodynamic Ensemble Prediction
.((((...{.(((((.(((((((.(.((.((..(((({(((((......)))))}.)))).)).)).)))))))).))))).}...).))).......
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that mir-639, when validated by TaqMan qPCR, exhibited low expression (Cq>30) or was not observed across all tested forensically relevant body fluids, including saliva, semen, venous blood, vaginal secretions, and menstrual blood [Wang et al. DOI:10.1111/1556-4029.12730].