Basic Information
Symbol
hsa-miR-639
RNA class
miRNA
mature miRNA
Alias
hsa-miR-639
MIR639
MicroRNA 639
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
Tissue/body fluid identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.10 kcal/mol
Thermodynamic ensemble
Free energy:
-45.58 kcal/mol
Frequency:
0.0903
Diversity:
9.95
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.((((...{.(((((.(((((((.(.((.((..(((({(((((......)))))}.)))).)).)).)))))))).))))).}...).))).......
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that miR-639, when validated by TaqMan qPCR, exhibited low expression (Cq>30) or was not observed across all tested forensically relevant body fluids, including saliva, semen, venous blood, vaginal secretions, and menstrual blood [Wang et al. DOI:10.1111/1556-4029.12730].