Basic Information

Symbol
hsa-mir-642a
RNA class
miRNA miRNA hairpin
Alias
MIR642A MicroRNA 642a Hsa-MiR-642a-5p Hsa-Mir-642 Hsa-MiR-642a-3p MicroRNA 642 MIRN642 MIR642 MicroRNA Mir-642a Hsa-Mir-642_pre Hsa-Mir-642a MIMAT0020924 MIMAT0003312 MI0003657 Mir-642a
Location (GRCh38)
6:18571784-18571880
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-642a
Sequence length
97 nt
GC content
0.5464

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-66.30 kcal/mol
Thermodynamic ensemble
Free energy: -66.88 kcal/mol
Frequency: 0.3883
Diversity: 2.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....(((((((((((.((((((((((((((((((((((.........)))))))))))))))))))))).)))))))))))(((....)))......
Thermodynamic Ensemble Prediction
....(((((((((((.{(((((((((((((((((((((.........)))))))))))))))))))))}.)))))))))))(((....)))......
Forensic Context

A study in humans demonstrated that the mir-642a-3p is upregulated 3.60-fold in postischemic left ventricular myocardium following acute ischemia during cardiac surgery [Saddic et al. DOI:10.1152/physiolgenomics.00049.2015]. A study in humans demonstrated that the mir-642a-3p was a common differentially expressed microRNA upregulated in the serum of patients at all three studied stages of atrial fibrillation [Wang et al. DOI:10.1016/j.hrtlng.2020.03.021].