Basic Information

Symbol
hsa-mir-650
RNA class
miRNA miRNA hairpin
Alias
MIR650 MicroRNA 650 Hsa-Mir-650 Hsa-MiR-650 MIRN650 MIMAT0003320 MI0003665
Location (GRCh38)
22:22822776-22822871
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-650
Sequence length
96 nt
GC content
0.6458

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.50 kcal/mol
Thermodynamic ensemble
Free energy: -36.87 kcal/mol
Frequency: 0.1081
Diversity: 12.05
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((((((((((...((((((.((((..((((((.(((.......))).))))))...)))))))))).)))))..........))))).......
Thermodynamic Ensemble Prediction
..(((({(((((...((((((.((((..((((((.(((.......})).))))))..,}))))))))).))))),,,......,))))).......
Forensic Context

A study in human postmortem prefrontal cortex demonstrated that the mir-650 was identified as a hub within a highly co-regulated network of 29 miRNAs specifically in depressed suicide subjects, where its expression showed a high degree of co-regulation across individuals that was not observed in non-psychiatric controls [Smalheiser et al. DOI:10.1371/journal.pone.0033201].