Basic Information

Symbol
hsa-mir-653
RNA class
miRNA miRNA hairpin
Alias
MIR653 MicroRNA 653 Hsa-Mir-653 Hsa-MiR-653-5p MIRN653 Hsa-Mir-653_pre Hsa-MiR-653-3p MIMAT0026625 MIMAT0003328 MI0003674 Mir-653
Location (GRCh38)
X:50008964-50009028
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-653
Sequence length
96 nt
GC content
0.3646

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.80 kcal/mol
Thermodynamic ensemble
Free energy: -34.14 kcal/mol
Frequency: 0.1139
Diversity: 3.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((((...((((((((((((((.(((((.(((((.............))))).))))).))))))))))))))...))))))............
Thermodynamic Ensemble Prediction
.((((((.{,((((((((((((((.(((((.(((((..,.......,..))))).))))).)))))))))))))).},))))))............
Forensic Context

A study in humans demonstrated that the mir-653-5p was upregulated 4 days post-burn in deep partial thickness burn skin compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in geriatric rats demonstrated that the mir-653-5p promotes apoptosis of cavernosal smooth muscle and endothelial cells, a process regulated by the long non-coding RNA ENSRNOT00000029245 [Song et al. DOI:10.3389/fendo.2022.1034043].