Basic Information

Symbol
hsa-mir-659
RNA class
miRNA miRNA hairpin
Alias
MIR659 MicroRNA 659 Hsa-MiR-659-3p Hsa-Mir-659 Hsa-MiR-659-5p MIRN659 MIMAT0022710 MIMAT0003337 MI0003683 Mir-659
Location (GRCh38)
9:109046229-109046298
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-659
Sequence length
97 nt
GC content
0.5361

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.60 kcal/mol
Thermodynamic ensemble
Free energy: -56.14 kcal/mol
Frequency: 0.0822
Diversity: 11.25
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...........(((...(((..(((((((((((((((((((((((((.......)))))))))))))))))))))))))..)))...))).......
Thermodynamic Ensemble Prediction
..,,{,.....{{,,,|{{{..(((((((((((((((((((((((((.,...,.)))))))))))))))))))))))))..}}}...}}}....,},
Forensic Context

A study in human denatured dermis from deep burn patients identified the mir-659 as significantly up-regulated, showing a 14.29-fold increase compared to normal skin [Liang et al. DOI:10.1016/j.burns.2011.10.014]. This differential expression profile, alongside other dysregulated miRNAs, provides an experimental basis for understanding the molecular mechanisms of functional recovery in thermal-injured skin [Wang and Zhou DOI:10.1007/s00438-024-02183-w].