Basic Information
Symbol
hsa-miR-1284
RNA class
miRNA
mature miRNA
Alias
hsa-miR-1284
MIR1284
MicroRNA 1284
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
Chronological age estimation
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.70 kcal/mol
Thermodynamic ensemble
Free energy:
-34.38 kcal/mol
Frequency:
0.5295
Diversity:
2.18
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
............((((((((.....((((((.((((((((...((((((((................))))))))...)))))))).)))))).)))))))).{{{{|...,})}}....
Forensic Context
A study in humans demonstrated that the miR-1284 is significantly positively correlated with age in peripheral blood, showing a positive correlation in a microarray cohort (array correlation 0.259) and being validated in a high-throughput sequencing cohort (NGS correlation 0.387, P value 0.003) [Meder et al. DOI:10.1373/clinchem.2014.224238]. A study in humans using massively parallel sequencing identified the miR-1284 as an absolute specific marker for venous blood, demonstrating high specificity across all pairwise comparisons and moderate expression levels [Liu et al. DOI:10.3390/genes13091530].