Basic Information

Symbol
hsa-mir-664a
RNA class
miRNA miRNA hairpin
Alias
MIR664A MicroRNA 664a Hsa-MiR-664a-3p Hsa-MiR-664a-5p Hsa-Mir-664 MicroRNA 664 MIRN664 MIR664 Hsa-Mir-664a MIMAT0005948 MIMAT0005949 MI0006442 Mir-664a
Location (GRCh38)
1:220200538-220200619
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Mechanical injury analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-664a
Sequence length
82 nt
GC content
0.3171

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-23.40 kcal/mol
Thermodynamic ensemble
Free energy: -24.38 kcal/mol
Frequency: 0.2047
Diversity: 15.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((((......((((.((((...(((.(((((((((.......))))))))).))))))).)))).....))))......
Thermodynamic Ensemble Prediction
...((((......((((.((((,,{(((.(((((((({.......}))))}))),))})))).)))).....))))......
Forensic Context

A study in humans demonstrated that the mir-664a-3p was downregulated in the plasma of patients with coronary artery disease compared to normal coronary artery controls, ranking among the top ten downregulated microRNAs identified via RNA sequencing [Zhong et al. DOI:10.1002/jcla.23020]. In a separate review encompassing human and animal models of traumatic brain injury, the mir-664a-3p was identified as a downregulated exosomal microRNA in the serum of patients with chronic mild traumatic brain injury [Li et al. DOI:10.1016/j.neuint.2023.105643].