Basic Information

Symbol
hsa-mir-1285-1
RNA class
miRNA miRNA hairpin
Alias
MIR1285-1 MicroRNA 1285-1 Hsa-MiR-1285-3p Hsa-MiR-1285-5p Hsa-Mir-1285-1 MIRN1285-1 MIMAT0005876 MIMAT0022719 MI0006346 hsa-mir-1285
Location (GRCh38)
17:19344506-19344574
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1285-1
Sequence length
84 nt
GC content
0.4762

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-57.80 kcal/mol
Thermodynamic ensemble
Free energy: -58.49 kcal/mol
Frequency: 0.3248
Diversity: 4.11
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((((((((((.(((((((((((((((((((((((.........,)}))))))))))))))))))))).))))))))))))..
Forensic Context

A study in humans demonstrated that hsa-miR-1285 was significantly increased in the plasma of male acute myocardial infarction patients compared to healthy controls, as identified by next-generation sequencing, though RT-qPCR validation in an independent cohort showed no significant difference [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. A separate review of human studies reported that hsa-miR-1285-3p was upregulated in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100].