A study in mice demonstrated that the mir-671 is a degradation target for miR-671 via AGO2, leading to its degradation [Patop et al. DOI:10.15252/embj.2018100836]. A study in mice demonstrated that the mir-671 degrades the circular RNA CDR1as via AGO2, and knockout of CDR1as leads to increased levels of the mir-671 alongside altered excitatory and behavioral phenotypes [Ines Lucia Patop et al. DOI:10.15252/embj.2018100836].