Basic Information

Symbol
hsa-mir-6716
RNA class
miRNA miRNA hairpin
Alias
MIR6716 MicroRNA 6716 Hsa-Mir-6716 MicroRNA Mir-6716 MIMAT0025845 MIMAT0025844 MI0022550
Location (GRCh38)
11:118644000-118644079
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-6716
Sequence length
80 nt
GC content
0.6000

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-30.40 kcal/mol
Thermodynamic ensemble
Free energy: -32.42 kcal/mol
Frequency: 0.0377
Diversity: 9.26
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.((((((...,..,..((((((((((((..((((((.........))))))..))})}))))))))..,....)).))))
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-6716-3p showing altered expression in deep partial thickness burn skin compared to normal skin at various post-burn timepoints [Siu et al. DOI:10.1111/wrr.13100]. A systematic review of human studies found that the mir-6716-3p is associated with traffic-related air pollution (TRAP) component exposure, specifically with PM10, PM2.5, black carbon, ultrafine particles, and NO2 in plasma [Kotsyfakis & Patelarou 10.1080/1354750X.2019.1652348].