Forensic Context

A study in humans demonstrated that hsa-miR-1285 was significantly increased in the plasma of male acute myocardial infarction patients compared to healthy controls, as identified by next-generation sequencing, though RT-qPCR validation in an independent cohort showed no significant difference [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. A separate review of human studies reported that hsa-miR-1285-3p was upregulated in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100].