Forensic Context

A study in human umbilical vein endothelial cells (HUVECs) demonstrated that the miR-675-5p was significantly upregulated (fold change 35.56) in exosomes derived from cells under heat stroke temperature conditions, identifying it as a potential noninvasive biomarker for heat stroke [Chen et al. DOI:10.12659/MSM.909983]. In a separate forensic investigation on human body fluids, the miR-675-5p was considered for menstrual blood identification but was not further investigated as its expression levels were below those of reference genes in the target body fluid [Sauer et al. DOI:10.1016/j.fsigen.2016.01.018].