Basic Information

Symbol
hsa-mir-676
RNA class
miRNA miRNA hairpin
Alias
MIR676 MicroRNA 676 Hsa-MiR-676-3p Hsa-Mir-676 Hsa-Mir-676_pre Hsa-MiR-676-5p MIMAT0018203 MIMAT0018204 MI0016436 Mir-676
Location (GRCh38)
11:79402022-79402109
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-676
Sequence length
67 nt
GC content
0.4478

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.40 kcal/mol
Thermodynamic ensemble
Free energy: -32.76 kcal/mol
Frequency: 0.5591
Diversity: 1.06
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in healthy human volunteers demonstrated that the mir-676-3p increased 2.99-fold in serum following recreational alcohol consumption, with this change being statistically significant [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128]. A study in mice demonstrated that the mir-676-3p is a radiation-sensitive miRNA in peripheral blood leukocytes, showing a positive linear correlation with irradiation dose at 48 hours post-exposure [Li et al. DOI:10.1177/15593258221123679]. In a separate investigation, the mir-676-3p was identified as a tissue injury marker, being downregulated in the irradiated lung tissue of both C3H and C57Bl/6 mouse strains following whole thorax irradiation [Rogers et al. DOI:10.1371/journal.pone.0232411].