Basic Information

Symbol
hsa-mir-6760
RNA class
miRNA miRNA hairpin
Alias
MIR6760 MicroRNA 6760 Hsa-Mir-6760 MicroRNA Mir-6760 MIMAT0027420 MIMAT0027421 MI0022605
Location (GRCh38)
12:111304142-111304209
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-6760
Sequence length
68 nt
GC content
0.6324

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.60 kcal/mol
Thermodynamic ensemble
Free energy: -35.11 kcal/mol
Frequency: 0.4343
Diversity: 2.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-6760-3p as a potential biomarker for recurrent myocardial infarction risk, demonstrating it was downregulated in whole blood of patients with recurrent MI compared to stable CAD controls after percutaneous coronary intervention, with this differential expression achieving significance after false-discovery rate correction (FDR <0.1) in the replication cohort [Onuoha et al. DOI:10.1111/cts.13307]. The investigation found that the mir-6760-3p was not significantly different in plasma samples, indicating whole blood may be the preferred sample source for miRNA profiling related to thrombotic risk prognosis.