Basic Information

Symbol
hsa-mir-1289-1
RNA class
miRNA miRNA hairpin
Alias
MIR1289-1 MicroRNA 1289-1 Hsa-Mir-1289-1 MIRN1289-1 MIMAT0005879 Hsa-MiR-1289 MI0006350 hsa-mir-1289
Location (GRCh38)
7:21471058-21471146
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Mechanical injury analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1289-1
Sequence length
144 nt
GC content
0.4167

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-53.80 kcal/mol
Thermodynamic ensemble
Free energy: -56.98 kcal/mol
Frequency: 0.0057
Diversity: 18.99
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((.......(((((((........(((...(((((((((.((((((.((((((((((................)))))))))).)))))).))))))))).....)))........)))))))...)))))))))..
Thermodynamic Ensemble Prediction
{((((((((.{{,...(((((((........,((,,,(((((((((.((((((.{(((((((((.,.,.....,,.....)))))))))}.)))))).))))))))}.....,,},.,.,,..)))))))}}.))))))))}..
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns validated in human skin tissue samples and cell lines using qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A study in humans identified the mir-1289 as having higher expression in the cerebrospinal fluid of comatose severe traumatic brain injury patients [Li et al. DOI:10.1016/j.neuint.2023.105643].