Basic Information

Symbol
hsa-mir-6771
RNA class
miRNA miRNA hairpin
Alias
MIR6771 MicroRNA 6771 Hsa-Mir-6771 MicroRNA Mir-6771 MIMAT0027442 MIMAT0027443 MI0022616
Location (GRCh38)
16:50292616-50292675
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-6771
Sequence length
60 nt
GC content
0.6500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-22.70 kcal/mol
Thermodynamic ensemble
Free energy: -23.46 kcal/mol
Frequency: 0.2931
Diversity: 4.57
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans with coronary artery disease demonstrated that the mir-6771-3p was downregulated in whole blood of patients with recurrent myocardial infarction after percutaneous coronary intervention, with this differential expression remaining significant after false-discovery rate correction (FDR <0.1) in a replication cohort [Onuoha et al. DOI:10.1111/cts.13307]. The investigation found no significant differential expression for the mir-6771-3p in plasma samples, and the research indicated that whole blood may be the preferred sample source for miRNA profiling related to thrombotic risk prognosis.