Basic Information

Symbol
hsa-mir-129-1
RNA class
miRNA miRNA hairpin
Alias
MIR129-1 MicroRNA 129-1 Hsa-MiR-129-1-3p Hsa-MiR-129-5p Hsa-Mir-129-1 MIRN129-1 Hsa-Mir-129-P2_pre MIMAT0004548 MIMAT0000242 Mir-129-1 MI0000252 MIR-129b
Location (GRCh38)
12:6964097-6964191
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden death from CNS diseases Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-129-1
Sequence length
72 nt
GC content
0.4861

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.50 kcal/mol
Thermodynamic ensemble
Free energy: -30.68 kcal/mol
Frequency: 0.1475
Diversity: 4.74
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A bioinformatics study in brown rats (Rattus norvegicus) identified 68 time-course differentially expressed microRNAs after spinal cord injury, with the mir-129-1 noted in the literature as being suppressed to induce overexpression of CDK6 and promote cell proliferation [Liu et al. DOI:10.1097/BRS.0000000000001323]. In methamphetamine research, the mir-129-1 was found to be upregulated in SH-SY5Y cells treated with METH and is a target of circ_0015891, implicating it in dopaminergic apoptosis [Xu et al. DOI:10.1007/S10571-023-01323-X].