Basic Information

Symbol
hsa-mir-6772
RNA class
miRNA miRNA hairpin
Alias
MIR6772 MicroRNA 6772 Hsa-Mir-6772 MicroRNA Mir-6772 MIMAT0027445 MIMAT0027444 MI0022617
Location (GRCh38)
Forensic tag(s)
Sudden cardiac death diagnosis

Sequence & Structure

Transcript ID
hsa-mir-6772
Sequence length
64 nt
GC content
0.6250

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-22.40 kcal/mol
Thermodynamic ensemble
Free energy: -24.11 kcal/mol
Frequency: 0.0619
Diversity: 15.72
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-6772-3p was selected for validation from RNA-seq data based on an area under the curve greater than 0.6 or involvement in plaque rupture/erosion mechanisms, but it showed no significant difference between plaque rupture and plaque erosion groups in the replication cohort [Li et al. DOI:10.1016/j.ygeno.2020.11.019]. A study in humans identified the mir-6772-3p as a potential biomarker for coronary artery disease, where it was found to be downregulated in patient plasma compared to normal coronary artery controls using RNA sequencing [Zhong et al. DOI:10.1002/jcla.23020].