Basic Information

Symbol
hsa-mir-129-2
RNA class
miRNA miRNA hairpin
Alias
MIR129-2 MicroRNA 129-2 Hsa-MiR-129-2-3p Hsa-MiR-129-5p Hsa-Mir-129-2 MIRN129-2 Hsa-Mir-129-P1_pre MIMAT0004605 MIMAT0000242 Mir-129-2 MI0000473 MIR-129b
Location (GRCh38)
11:43581394-43581483
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-129-2
Sequence length
90 nt
GC content
0.5333

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-48.60 kcal/mol
Thermodynamic ensemble
Free energy: -49.11 kcal/mol
Frequency: 0.4370
Diversity: 3.97
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in rats demonstrated that the mir-129-2 is a differentially expressed microRNA in cavernous nerve injury erectile dysfunction (CNI-ED) [Huang et al. DOI:10.1080/21655979.2021.1973863]. In spinal cord injury (SCI) research, the mir-129-2 is downregulated in rodent models, and its expression correlates with functional recovery scores, suggesting a role in pathophysiology and potential as a severity correlate [Nieto-Diaz et al. DOI:10.3389/fncel.2014.00053]. In human postmortem prefrontal cortex, the mir-129-2 was found to be down-regulated in subjects with schizophrenia [Smalheiser et al. DOI:10.1371/journal.pone.0086469].