Basic Information

Symbol
hsa-mir-6857
RNA class
miRNA miRNA hairpin
Alias
MIR6857 MicroRNA 6857 Hsa-Mir-6857 MicroRNA Mir-6857 MIMAT0027615 MIMAT0027614 MI0022703
Location (GRCh38)
X:53405673-53405765
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-6857
Sequence length
93 nt
GC content
0.5699

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-27.40 kcal/mol
Thermodynamic ensemble
Free energy: -30.23 kcal/mol
Frequency: 0.0101
Diversity: 13.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...(((.(((((..((.((((..(((((....(((((........(((......))).....)))))..))))).)))).))..)))))))).
Thermodynamic Ensemble Prediction
...((,{(((((..((.((((..(((((....(((({.........,{......},}...}.))))),.))))).)))).))..)))))))),
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-6857-3p showing altered expression in human skin tissue post-burn and in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans identified 181 differentially expressed circulating miRNAs in plasma from acute myocardial infarction patients, with the mir-6857-3p being one of the top ten downregulated miRNAs [Zhong et al. DOI:10.1002/jcla.23099].